Medications and Potential Visual Side Effects

Medication   Potential Effects on the Eye 

5-FU (fluorouoracil)  Inflammation of the eyelids
Irritation of the eyes
Scarring within the eye 

Accutane ® (isotretinoin)  Reduced vision
Inflammation of the cornea
Corneal opacities
Inflammation of the eyelids
Redness in and around the eye
Inflammation of the optic nerve
Dry eyes
Sensitivity to light
Night blindness 

Actonel ® (risedronate)  Inflammation in the eye
Eye pain
Blurred vision 

Adalat ® (nifedipine)  Sensitivity to light
Decreased vision
Swelling in and around the eye 

Adriamycin PFS/RDF (doxorubicin)  Red, swollen eyes
Tear production
Blurred vision 

Amitriptyline  Dilated pupils
Inability to focus
Dry eyes
Sensitivity to light 

Aredia ® (pamidronate)  Inflammation in the eye
Eye pain
Blurred vision 

Aspirin   Occasional blurred vision
Changes in vision
Double vision
Sensitivity to light
Dry eyes
Color vision problems 

Ativan ® (lorazepam)  Double vision
Twitching of the eyes
Decreased corneal reflex
Redness of the eye 

Atropine  Dilated pupils
Absence of reaction to light 

Benadryl ® (diphenhydramine)  Changes in pupil size
Decreased vision
Dry eye 

BiCNU ® (carmustine)  Glaucoma
Paralysis of the eye muscles
Swelling of the optic nerve 

Bitter orange (citrus aurantium)  Damage by UV light 

Blenoxane ® (bleomycin)  Red, swollen eyes
Tear production
Blurred vision 

Calan ® (verapamil)  Sensitivity to light
Decreased vision
Swelling in and around the eye 

Capoten ® (captopril)  Decreased vision
Inflammation of the eye
Inflammation of the eyelid
Sensitivity to light
Welts around the eye 

Chamomile (matricaria chamomilla)  Inflammation in the eye 

Chlor-Trimeton ® (chlorpheniramine)  Changes in pupil size
Decreased vision
Dry eye 

Cialis ® (tadalafil)  Problems with color vision
Increased sensitivity to light
Blurred vision
Eye pain 

Ciprofloxacin   Glare
Sensitivity to light 

Cisplatin ® (cisplatinum)  Vision loss
Blurred vision
Color deficiency
Swelling of the optic disc 

Claritin ® (loratidine)  Excess tears
Dry eyes
Contact lens discomfort 

Combivir ® (lamivudine/zidovudine)  Macular edema (swelling)
Excessive growth of hair
Excessive pigment in the eyelids and whites of the eye 

Cordarone ® (amiodarone)  Sensitivity to light
Keratopathy
Damage to the optic nerve 

Coreg ® (carvedilol)  Reduced tear secretion
Visual disturbances
Reddening of the eyes
Sensitivity to light
Double vision 

Cortisone   Cataracts
Elevated pressure inside the eye
Sensitivity to light
Enlarged pupils
Decreased vision 

Cytovene ® (ganciclovir)  Abnormally low eye pressure
Retinal detachment
Increased eye pressure cataracts 

Dexedrine ®  Dilated pupils
Pupils slow to respond to changes in light 

Didronel ® (etidronate)  Inflammation in the eye
Eye pain
Blurred vision 

Digitoxin ®  Changes in color vision
visual disturbances
glare 

Dilantin ® (phenytoin)  Paralysis of external eye muscles
Double vision
Uncontrollable eye movement 

Fosamax ® (alendronate)  Inflammation in the eye
Eye pain
Blurred vision 

Ginkgo Biloba  Hemorrhage in the eye 

Henbane (hyoscyamus niger)  Inability to focus
Dilated pupils 

Hydrocortisone   Cataracts
Elevated pressure inside the eye
Sensitivity to light
Enlarged pupils
Decreased vision 

HydroDiuril ® (hydrochlorothiazide)  Sensitivity to light
Nearsightedness
Reduced tear production
Changes in color vision 

Ibuprofen   Occasional blurred vision
Changes in vision
Double vision
Sensitivity to light
Dry eyes
Color vision problems  

Imipramine   Dilated pupils
Inability to focus
Dry eyes
Sensitivity to light 

Inderal ® (propranolol)  Reduced tear secretion
Visual disturbances
Reddening of the eyes
Sensitivity to light
Double vision 

Kava Kava (piper methysticum)  Inability to focus 

Lamictal ® (lamotrigine)  Double vision
Blurred vision
Involuntary movement of the eyes 

Lanoxin ® (digoxin)  Changes in color vision
visual disturbances
glare 

Lasix ® (furosemide)  Sensitivity to light
Nearsightedness
Reduced tear production
Changes in color vision 

Levitra ® (vardenafil)  Problems with color vision
Increased sensitivity to light
Blurred vision
Eye pain 

Lopressor ® (metoprolol)  Reduced tear secretion
Visual disturbances
Reddening of the eyes
Sensitivity to light
Double vision 

Mandrake (mandragora officinarum)  Dilated pupils

Mellaril ® (thioridazine)  Dilated pupils
Increased incidence of cataracts

Methamphetamine   Dilated pupils
Pupils slow to respond to changes in light 

Methotrexate  Swelling of the eyelids
Swelling around the eyes
Excess blood in the eye
Increased tear production
Sensitivity to light 

Myleran ® (busulfan)  Cataracts
Redness and burning of the eyes
Loss of eyelashes or eyebrows 

Neurontin ® (gabapentin)  Double vision
Blurred vision
Involuntary movement of the eyes 

Niacin   Dry eyes 

Nolvadex ® (tamoxifen)  Vision loss
Retinal swelling
Retinal hemorrhage
Swelling of the optic disc
Swelling of the macula
Retinal changes 

Norfloxacin   Glare
Sensitivity to light 

Norvasc ® (amlodipine)  Reduced tear secretion
Visual disturbances
Reddening of the eyes
Sensitivity to light
Double vision 

Ofloxacin  Glare
Sensitivity to light 

Procardia ® (nifedipine)  Sensitivity to light
Decreased vision
Swelling in and around the eye 

Propolis   Inflammation in the eye 

Prozac ® (fluoxetine)  Dilated pupils
Sensitivity to light 

Retrovir ® (zidovudine)  Macular edema (swelling)
Excessive growth of hair
Excessive pigment in the eyelids and whites of the eye 

Ritalin ® (methyliphenidate)  Dilated pupils
Pupils slow to respond to changes in light 

St. John's Wort (hypericum perforatum)  Sensitivity to light 

Tenormin ® (atenolol)  Reduced tear secretion
Visual disturbances
Reddening of the eyes
Sensitivity to light Double vision 

Thorazine ® (chlorpromazine)  Dilated pupils
Increased incidence of cataracts 

Transderm Scop ® (scopolamine)  Dilated pupils 

Valerian (valeriana officinalis)  Dilated pupils 

Valium ® (diazepam)  Double vision
Twitching of the eyes
Decreased corneal reflex
Redness of the eye 

Vasotec ® (enalapril)  Decreased vision
Inflammation of the eye
Inflammation of the eyelid
Sensitivity to light
Welts around the eye 

Viagra ® (sildenafil)  Problems with color vision
Increased sensitivity to light
Blurred vision Eye pain 

Videx ® (didanosine)  Retinal toxicity
Inflammation of the optic nerve
Night blindness 

Xanax ® (alprazolam)  Double vision
Twitching of the eyes
Decreased corneal reflex
Redness of the eye 

Zyrtec ®  excess tears
dry eyes
contact lens discomfort 

 

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